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Tuesday, October 24, 2006
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Entocort (budesonide)Entocort (budesonide) is glucocorticosteroid for inflammatory bowel diseases.ntocort is available as an oral controlled-release formulation of budesonide, Entocort capsules, for the treatment of Crohn's disease, and also as Entocort enema for topical treatment of ulcerative colitis.Entocort is available in the US (as Entocort EC) and is registered in more than 40 countries.ec entocort
Did you know?AstraZeneca has a ranga href="http://www.entocortec.com/c/home.asp">entocort
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effects entocort sidee of product specific and disease area websites for international healthcare professionals and patientocort
ents. Links to this information aentocort
re provided in the table below.Information forHealthcare professionalsPatients and familiesopens in a new windowLinks to country-specific websites can be found using the AstraZeneca websites list.If you still have a question regarding our drug portfolio you can Contact us.Entocort EC (budenoside) Frequently Asked QuestionsFrom Amber J. Tresca,Your Guide to Inflammatory Bowel Disease.FREE Newsletter. Sign Up Now!What is Entocort ec entocort
EC?Entocort EC is used to treat mild to moderate Crohn's disease involving the ileum and/or the ascending colon. Entocort EC is a nonsystemic corticosteroid that is released into the intestine and works toentocort
reduce inflammation. Because 90% of the drug is released in the intestine and not into the bloodstream, it ec entocort
causes fewer side effects than other corticosteroids (i.e., prednisone).How is Entocort EC taken?Entocort EC is normally taken in capsue form in the morning with or without foa href="http://www.entocortec.com/c/home.asp">entocort
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effects entocort sideod. Entocort EC should be swallowed whole and should never be crushed, chewed or broken in half.Why is Entocort EC prescribed?Even though Entocort EC beloentocort
ngs to the class of drugs known as corticosteroids, it may be more efffective and have fewer side effects than other medications in this category.What do I do if I miss a dose?If you miss a dose, take it as soon as you remember. If your ec entocort
next dose should be taken soon, just take that dose. Don't double up, or take more than one dose at a time.Who should not take Entocort EC?Tell your doctor if you have ever had any of the following conditions: a href="http://www.entocortec.com/c/home.asp">entocort
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effects entocort side * Any condition that supresses the immune system * Cataracts * Dentocort
iabetes (or a family history) * Glaucoma (or a family history) * High blood pressure * Liver disease * Osentocort
teoporosis * Tuberculosis * UlcersWhat are the side effects?Common side effects of Entocort EC include headache, respiratory infection, and nausea.Are there any sexual side effects?Entocort EC is not known to cause any sexual side effects in either men or women.What medications can Entocort EC interact with?Ketoconazole can intefere with the way the liver processes Entocort EC.Are there any food interactions?Grapefruit or grapefruit juice can interact with Entocort EC and cause more of it to be released into the bloodstream.Is Entocoec entocort
rt EC safe during pregnancy?The FDA has classified Entocort EC as a type C drug. The effect that Entocort EC has on an unborn centocort
hild has not been studied extensively. Entocort EC should only be used during pregnancy if clearly needed. Notify the prescribing doctor if you become pregnant while taking Entocoec entocort
rt EC. Entocort EC does pass into breast milk and can affect a nursing infant.a href="http://www.entocortec.com/c/home.asp">entocort
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effects entocort sideHow long is it safe to use Entocort EC?Entocort EC has been approved for use for up to 8 weeks.Is there anything else I should know about Entocort EC?People taking Entocort EC should avoid exposure to anyone who has chickenpox or the measles or who has been vaccinated with a live virus. Entocort may also suppress ec entocort
the response of the hypothalamus-pituitary-adrenal (HPA), and therapy may be necessary before surgery (including dental surgery) or other stressful events.GENERIC desonideBRAND NAME: Entocort ECDRUG CLASS AND MECHANISM: Budesonidentocort
e is a synthetic steroid of the glucocorticoid family. The naturally-occurring hormone whose actions budesonide mimics, is cortisol or hydrocortisone which is produced by the adrenal glands. Glucocorticoid steroids ec entocort
have potent anti-inflammatory actions. Crohn's disease is a chronic inflammatory bowel disease of unknown cause that results in diarrhea, crampy abdominal pain, ec entocort
fever and bleeding from the rectum. The active ingredient in Ententocort
ocort EC, budesonide, is released from granules in the ileum of the small intestine and the right (proximal) colon, where the inflammation of Crohn's disease occurs. Budesonide acts directly by contact with the ileum and colon. The budesonide that is absorbed into the body travels to the liver where it is broken-down and eliminated from the body. This prevents the majority of the absorbed drug from being distributed to the rest of the body. As a result, budesonide causes fewer severe side effects ec entocort
throughout the body than othentocort
er corticosteroids. The FDA approved Entocort EC in October of 2001.PRESCRIPTION: YesGENERIC AVAILABLE: NoPREPARATIONS: Capsules: 3mgSTORAGE: Capsules should be stored between 15-30ȃ (59-86Ȇ)PRESCRIBED FORec entocort
: Budesonide is used for the treatment of mild-to-moderately-active a href="http://www.entocortec.com/c/home.asp">entocort
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effects entocort sideCrohn's disease involving the ileum (the second half of the small intestine) and/or ascending colon (the beginning of the large intestine). It also is approved for maintaining remissions for up to three months.DOSING: Budesonide usually is taken once daily for up to eight weeks.DRUG INTERACTIONS: Medicines which block the liver enzymes tentocort
hat break down budesonide may lead to higher blood concentrations and more side effects. Such medications include ketoconazole (Nizoral), fluconazole (Diflucan), itraconazole (Sporanox), clarithromycin (Biaxin), erythromycin, verapamil (e.g. Calan; Isoptin; Covera HS), diltiazem (e.g. Cardizemec entocort
; Dilacor), ritonavir (Norvir; Kaletra), indinavir (Crixivan), and saquinavir (Invirase, Fortovase). Grapefruit juice has the same effect and should not be drunk by patients taking budesonide.PREGNANCY: Glucocorticoids taken orally that are similar to budesonide have been shown to cause fetal abnormalities in animals.entocort
It is not ec entocort
known if there is an increased risk of malformation in children born to mothers exposed to budesonide during pregnancy.NURSING MOTHERS: Glucocorticosteroids are secreted in human milk. Because of the potential for adverse reactions in nursing infants from any corticosteroid, a decision should be made whether to discontinue nursing or discontinue the budesonide. ec entocort
The amount of budesonide secreted in breast milk has not been determined.SIDE EFFECTS: Budesonide generally is well tolerated. The most common side effects are headache (1 in 5 patients), respiratory infection (1 in 10 patients), nausea (1 in 10 patients)entocort
, and symptoms or signs of too much corticosteroid. In the latter case, acne occurs in about 1 in 6 patients, easy bruising in 1 in 6 patients, moon (rounded) faces in 1 in 10 patients, and swollen ankles in 1 in 14 patients.High doses of glucocorticoids may decrease the formation and increase the breakdown of bone. Higher doses also may suppress the body's ability to make its own natural glucocorticoid, cortisol. It is possible that thentocort
ese effects are shared by budesonide. People with suppressed production of cortisol (which can bea href="http://www.entocortec.com/c/home.asp">entocort
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effects entocort side tested for by the doctor) need increased amounts of glucocorticoids, probably by the oral or intravenous route during periods of high physical stress. Important InformationENTOCORTàEC (budesonide) Capsules is used to treat ec entocort
mild to moderate active Crohn's disease, affecting the last part of the small intestine (called the ileum) and the first part of the large intestine (called the ascending colon). Individual results may vary. Entocort EC is not for everyone. Only your health care provider can determine if Entocort EC is right for you. * Do not take ENTOCORT EC if you have had an allergic reaction to ENTOCORT EC or any of its ingredients * Patients who take ENTOCORT EC may require supplemental treatment ec entocort
with a systemic glucocorticosteroid if they are undergoing surgery or are subject to other stress situations * If you are switching to ENTOCORT EC from a systemic glucocorticosteroid (such as prednisone), carefully follow your doctorɓ / health care providerɓ instructions. This will help you avoid health risks that may be linked entocort
with stopping a href="http://www.entocortec.com/c/home.asp">entocort
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* Patients who take ENTOCORT EC should avoid people with infections, including chickenpox and measlesThe most common side effects of ENTOCORT EC are headache, infection inec entocort
your air passages (respiratory infection), nausea, and symptoms of hypercorticism (too much steroids in your body).Please read the important Patient Product Information about ENTOCORT EC and discuss it with your health care provider.
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